Sucralose
Medium ConcernAlso known as
The concern
WHO 2023 guidelines advise against non-sugar sweeteners. A 2023 study in the Journal of Toxicology and Environmental Health found sucralose-6-acetate (a gut metabolite) is genotoxic. May disrupt gut microbiome balance.
What to look for on labels
This ingredient may appear under any of the following names or codes on product labels:
- Sucralose
- sucralose
- e955
- splenda
Learn more
Read the full evidence directly from the authoritative source.
View source: WHO / Journal of ToxicologyCommonly found in
Diet drinks, sugar-free gum, low-calorie yogurts, snack bars
Other artificial sweeteners to know about
Aspartame
MEDIUMIARC classified aspartame as a Group 2B possible carcinogen in July 2023, noting limited evidence of liver cancer in humans.
Saccharin
LOWCaused bladder cancer in male rats at high doses, triggering a 1977 US ban that was later reversed.
Acesulfame Potassium
LOWLimited long-term safety data.
Data sourced from IARC, FDA, EFSA, WHO and EWG public data. For informational purposes only. This does not constitute medical or legal advice.