Blue 2 (Indigotine)
Medium ConcernAlso known as
The concern
Animal studies showed statistically elevated brain tumour rates in male rats. EWG rates it with moderate concern. FDA considers current evidence insufficient to ban.
What to look for on labels
This ingredient may appear under any of the following names or codes on product labels:
- Blue 2 (Indigotine)
- blue 2
- indigotine
- e132
- fd&c blue no. 2
- fd&c blue 2
Commonly found in
Sweets, soft drinks, cereals, ice cream, sauces, confectionery
Other artificial colours to know about
Red 3 (Erythrosine)
HIGHFDA banned Red 3 in food and ingested drugs in January 2025 after studies showed it causes thyroid tumours in male rats.
Red 40 (Allura Red)
MEDIUMOne of the "Southampton Six" food dyes.
Yellow 5 (Tartrazine)
MEDIUMSouthampton Six dye linked to hyperactivity in children.
Yellow 6 (Sunset Yellow)
MEDIUMSouthampton Six dye.
Data sourced from IARC, FDA, EFSA, WHO and EWG public data. For informational purposes only. This does not constitute medical or legal advice.